ULTOMIRIS is a medicine that affects your immune system and can lower the ability of your immune system to fight infections.
Administration and Dosage:
ULTOMIRIS may be administered as an intravenous infusion (ULTOMIRIS vial for intravenous administration) in adult or pediatric patients one month of age and older or as a subcutaneous injection for maintenance (ULTOMIRIS on-body delivery system for subcutaneous administration) in adult patients.
Vials are intended for intravenous use only, and on-body delivery systems (prefilled cartridge and on-body injector) are intended for subcutaneous maintenance use only.
Common Side Effects:
The most common side effects of ULTOMIRIS in people treated for aHUS are upper respiratory tract infection, diarrhea, nausea, vomiting, headache, high blood pressure and fever.
The most common side effects of subcutaneous administration of ULTOMIRIS in adults treated for aHUS are local injection site reactions.
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ULTOMIRIS is a prescription medicine used to treat:
- adults and children 1 month of age and older with a disease called atypical Hemolytic Uremic Syndrome (aHUS). ULTOMIRIS is not used in treating people with Shiga toxin E. coli related hemolytic uremic syndrome (STEC-HUS).
- adults with aHUS when administered subcutaneously (under your skin).
It is not known if ULTOMIRIS is safe and effective in children younger than 1 month of age.
Subcutaneous administration of ULTOMIRIS has not been evaluated and is not approved for use in children.